Rajiv Phondu Gude, Ph.D.
Advanced Centre for Treatment Research and Education in Cancer
Gude Lab
Khanolkar Shodhika, Tata Memorial Centre, Kharghar
Navi Mumbai - 410 210
Maharashtra
E-mail: rpgude@actrec.gov.in
Phone: +91-22 -27405000
Fax: +91-22 -27412892,93,94
URL: http://actrec.gov.in/pi-webpages/RajivGude/drgude.html
Area of Specialization:
Molecular Oncology
Publications:
1.
Jain, M., Ratheesh, A. and Gude, R. P . Pentoxifylline inhibits integrin-mediated adherence of 12(S)-HETE and TNFalpha-activated B16F10 cells to fibronectin and endothelial cells. Chemotherapy. 2010. 56, 82-88. [PubMed]
2.
Shenoy, V. S., Gude, R. P. and Murthy, R. S. Paclitaxel-loaded glyceryl palmitostearate nanoparticles: in vitro release and cytotoxic activity. Journal of Drug Targeting. 2009. 17, 304-310. [PubMed]
3.
Shenoy, V. S., Rajyaguru, T. H., Gude, R. P. and Murthy, R. S. Studies on paclitaxel-loaded glyceryl monostearate nanoparticles. Journal of Microencapsulation. 2009. 26, 471-478. [PubMed]
4.
Dua, P. and Gude, R. P. Pentoxifylline impedes migration in B16F10 melanoma by modulating Rho GTPase activity and actin organisation. European Journal of Cancer. 2008. 44, 1587-1595. [PubMed]
5.
Ratheesh, A., Ingle, A. and Gude, R. P . Pentoxifylline modulates cell surface integrin expression and integrin mediated adhesion of B16F10 cells to extracellular matrix components. Cancer Biology & Therapy. 2007. 6, 1743-1752. [PubMed]
6.
Dua, P., Ingle, A. and Gude, R. P. Suramin augments the antitumor and antimetastatic activity of pentoxifylline in B16F10 melanoma. International Journal of Cancer. 2007. 121, 1600-1608. [PubMed]
7.
Dua, P. and Gude, R. P. Antiproliferative and antiproteolytic activity of pentoxifylline in cultures of B16F10 melanoma cells. Cancer Chemotherapy and Pharmacology. 2006. 58, 195-202. [PubMed]
8.
Sant, V. P., Nagarsenker, M. S., Rao, S. G. and Gude, R. P. Sterically stabilized etoposide liposomes: evaluation of antimetastatic activity and its potentiation by combination with sterically stabilized pentoxifylline liposomes in mice. Cancer Biotherapy & Radiopharmaceuticals. 2003. 18, 811-817. [PubMed]
9.
Shukla, V. and Gude, R. P. Amelioration of B16F10 melanoma cells induced oxidative stress in DBA/2 mice by pentoxifylline. Journal of Experimental & Clinical Cancer Research : CR. 2003. 22, 407-410. [PubMed]
10.
Shukla, V. and Gude, R. P. Potentiation of antimetastatic activity of pentoxifylline in B16F10 and B16F1 melanoma cells through inhibition of glutathione content. Cancer Biotherapy & Radiopharmaceuticals. 2003. 18, 559-564. [PubMed]
11.
Shukla, V. and Gude, R. P . Potentiation of lipid peroxidation in B16F10 and B16F1 melanoma cells by caffeine, a methylxanthine derivative: relationship to intracellular glutathione. Chemotherapy. 2003. 49, 71-75. [PubMed]
12.
Menon, L. G., Ingle, A. D. and Gude, R. P. Tumor regression of B16F10 melanoma in vivo by prevention of neovascularization: study on theophylline. Cancer Biotherapy & Radiopharmaceuticals. 2002. 17, 213-217. [PubMed]
13.
Gude, R. P., Jadhav, M. G., Rao, S. G. and Jagtap, A. G. Effects of niosomal cisplatin and combination of the same with theophylline and with activated macrophages in murine B16F10 melanoma model. Cancer Biotherapy & Radiopharmaceuticals. 2002. 17, 183-192. [PubMed]
14.
Gude, R. P. , Binda, M. M., Boquete, A. L. and Bonfil, R. D. Inhibition of endothelial cell proliferation and tumor-induced angiogenesis by pentoxifylline. Journal of Cancer Research and Clinical Oncology. 2001. 127, 625-630. [PubMed]
15.
Gude, R. P. , Menon, L. G. and Rao, S. G. Effect of Caffeine, a xanthine derivative, in the inhibition of experimental lung metastasis induced by B16F10 melanoma cells. Journal of Experimental & Clinical Cancer Research. 2001. 20, 287-292. [PubMed]
16.
Sant, V. P., Nagarsenker, M. S., Rao, S. G. and Gude, R. P. Enhancement of anti-metastatic activity of pentoxifylline by encapsulation in conventional liposomes and sterically stabilized liposomes in murine experimental B16F10 melanoma model. The Journal of Pharmacy and Pharmacology. 2000. 52, 1461-1466. [PubMed]
17.
Gaikwad, S. Y., Jagtap, A. G., Ingle, A. D., Ra, S. G. and Gude, R. P. Antimetastatic efficacy of niosomal pentoxifylline and its combination with activated macrophages in murine B16F10 melanoma model. Cancer Biotherapy & Radiopharmaceuticals. 2000. 15, 605-615. [PubMed]
18.
Gude, R. P. , Binda, M. M., Presas, H. L., Klein-Szanto, A. J. and Bonfil, R. D. Studies on the mechanisms responsible for inhibition of experimental metastasis of B16-F10 murine melanoma by pentoxifylline. Journal of Biomedical Science. 1999. 6, 133-141. [PubMed]
19.
Gude, R. P ., Ingle, A. D. and Rao, S. G. Inhibition of lung homing of B16F10 by pentoxifylline, a microfilament depolymerizing agent. Cancer Letters. 1996. 106, 171-176. [PubMed]
20.
Gude, R. P. , Chitnis, M. P. and Rao, S. G. Effect of pentoxifylline, a multidrug resistance reversal agent, on haemopoietic stem cell homing. Cell Biology International. 1994. 18, 79-84. [PubMed]
21.
Chitnis, M. P., Menon, R. S. and Gude, R. P. Effect of Tween 80 on adriamycin cytotoxicity in murine P388 leukemia. Tumori. 1984. 70, 313-315. [PubMed]
22.
Chitnis, M. P., Joshi, S. S., Gude, R. P. and Menon, R. S. Induced resistance in leukaemia L1210 to adriamycin and its cross-resistance to vincristine and bouvardin. Chemotherapy. 1982. 28, 209-212. [PubMed]
Last modified on : Mar 4, 2011