INCREDB ID : 371
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Aditi Chatterjee, Ph.D.
Faculty Scientist 
 
Institute of Bioinformatics
Discoverer Building, International Tech Park, Whitefield
Bangalore - 560 066   
Karnataka   
 
E-mail: aditi@ibioinformatics.org
 
URL: http://www.ibioinformatics.org/team.htm
 
Positions Held:
Position Affiliation Time Period
Faculty Scientist Institute of Bioinformatics, Bangalore, India 2011-Present
Instructor Department of Otolaryngology, Johns Hopkins School of Medicine, Baltimore, MD, USA. 2008-2011
Senior Post Doctoral Fellow Department of Otolaryngology, Johns Hopkins School of Medicine, Baltimore, MD, USA. 2006-2008
Research Scientist Institute of Bioengineering and Nanotechnology, Biopolis, Singapore 2005-2006
Post Doctoral Fellow Department of Otolaryngology, Johns Hopkins School of Medicine, Baltimore, MD, USA. 2002-2005
Post Doctoral Fellow Department of Oncology, Johns Hopkins School of Medicine, Baltimore, MD, USA. 2001-2002
Training Research Fellow Johns Hopkins School of Medicine, Baltimore, MD, USA. 2000-2001
 
Area of Specialization:
Cancer Biology; Gene silencing; Signalling Pathways; Genomics and proteomics
Research Summary:
Effect of cigarette smoke and other envioremental carcinogens on progression of several cancer types
Role of mitochondria in cancer progression
Genomic approaches to identify genetic anomilies in cancer
Proteomic approaches to study abarent signalling in cancer
 
Publications:
1. Chang, X., Ravi, R., Pham, V., Bedi, A., Chatterjee, A. and Sidransky, D.  Adenylate kinase 3 sensitizes cells to cigarette smoke condensate vapor induced Cisplatin resistance. PloS One. 2011.  6, e20806. [PubMed]
2. Chatterjee, A., Dasgupta, S. and Sidransky, D.  Mitochondrial subversion in cancer. Cancer Prevention Research. 2011.  4, 638-654. [PubMed]
3. Sen, T., Sen, N., Brait, M., Begum, S., Chatterjee, A., Hoque, M. O., Ratovitski, E. and Sidransky, D.  DeltaNp63alpha confers tumor cell resistance to cisplatin through the AKT1 transcriptional regulation. Cancer Research. 2011.  71, 1167-1176. [PubMed]
4. Sen, T., Chang, X., Sidransky, D. and Chatterjee, A.  Regulation of DeltaNp63alpha by NFkappaBeta. Cell Cycle. 2010.  9, 4841-4847. [PubMed]
5. Chatterjee, A., Chang, X., Sen, T., Ravi, R., Bedi, A. and Sidransky, D.  Regulation of p53 family member isoform DeltaNp63alpha by the nuclear factor-kappaB targeting kinase IkappaB kinase beta. Cancer Research. 2010.  70, 1419-1429. [PubMed]
6. Chatterjee, A., Sen, T., Chang, X. and Sidransky, D.  Yes-associated protein 1 regulates the stability of DeltaNp63alpha. Cell Cycle. 2010.  9, 162-167. [PubMed]
7. Chatterjee, A., Upadhyay, S., Chang, X., Nagpal, J. K., Trink, B. and Sidransky, D.  U-box-type ubiquitin E4 ligase, UFD2a attenuates cisplatin mediated degradation of DeltaNp63alpha. Cell Cycle. 2008.  7, 1231-1237. [PubMed]
8. Zhou, S., Kachhap, S., Sun, W., Wu, G., Chuang, A., Poeta, L., Grumbine, L., Mithani, S. K., Chatterjee, A., Koch, W., Westra, W. H., Maitra, A., Glazer, C., Carducci, M., Sidransky, D., McFate, T., Verma, A. and Califano, J. A.  Frequency and phenotypic implications of mitochondrial DNA mutations in human squamous cell cancers of the head and neck. Proceedings of the National Academy of Sciences of the United States of America. 2007.  104, 7540-7545. [PubMed]
9. Upadhyay, S., Chatterjee, A., Trink, B., Sommer, M., Ratovitski, E. and Sidransky, D.  TAp63gamma regulates hOGG1 and repair of oxidative damage in cancer cell lines. Biochemical and Biophysical Research Communications. 2007.  356, 823-828. [PubMed]
10. Wu, G., Guo, Z., Chatterjee, A., Huang, X., Rubin, E., Wu, F., Mambo, E., Chang, X., Osada, M., Sook, K. i. m., Moon, C., Califano, J. A., Ratovitski, E. A., Gollin, S. M., Sukumar, S., Sidransky, D. and Trink, B.  Overexpression of glycosylphosphatidylinositol (GPI) transamidase subunits phosphatidylinositol glycan class T and/or GPI anchor attachment 1 induces tumorigenesis and contributes to invasion in human breast cancer. Cancer Research. 2006.  66, 9829-9836. [PubMed]
11. Chatterjee, A., Mambo, E., Zhang, Y., Deweese, T. and Sidransky, D.  Targeting of mutant hogg1 in mammalian mitochondria and nucleus: effect on cellular survival upon oxidative stress. BMC Cancer. 2006.  6, 235. [PubMed]
12. Upadhyay, S., Liu, C., Chatterjee, A., Hoque, M. O., Kim, M. S., Engles, J., Westra, W., Trink, B., Ratovitski, E. and Sidransky, D.  LKB1/STK11 suppresses cyclooxygenase-2 induction and cellular invasion through PEA3 in lung cancer. Cancer Research. 2006.  66, 7870-7879. [PubMed]
13. Hoque, M. O., Begum, S., Topaloglu, O., Chatterjee, A., Rosenbaum, E., Van, C., Westra, W. H., Schoenberg, M., Zahurak, M., Goodman, S. N. and Sidransky, D.  Quantitation of promoter methylation of multiple genes in urine DNA and bladder cancer detection. Journal of the National Cancer Institute. 2006.  98, 996-1004. [PubMed]
14. Zhang, H., Chatterjee, A. and Singh, K. K.  Saccharomyces cerevisiae polymerase zeta functions in mitochondria. Genetics. 2006.  172, 2683-2688. [PubMed]
15. Chatterjee, A., Mambo, E., Osada, M., Upadhyay, S. and Sidransky, D.  The effect of p53-RNAi and p53 knockout on human 8-oxoguanine DNA glycosylase (hOgg1) activity. The FASEB Journal . 2006.  20, 112-114. [PubMed]
16. Kim, M. M., Glazer, C. A., Mambo, E., Chatterjee, A., Zhao, M., Sidransky, D. and Califano, J. A.  Head and neck cancer cell lines exhibit differential mitochondrial repair deficiency in response to 4NQO. Oral Oncology. 2006.  42, 201-207. [PubMed]
17. Wu, G., Xing, M., Mambo, E., Huang, X., Liu, J., Guo, Z., Chatterjee, A., Goldenberg, D., Gollin, S. M., Sukumar, S., Trink, B. and Sidransky, D.  Somatic mutation and gain of copy number of PIK3CA in human breast cancer. Breast Cancer Research : BCR. 2005.  7, R609-16. [PubMed]
18. Mambo, E., Chatterjee, A., Xing, M., Tallini, G., Haugen, B. R., Yeung, S. C., Sukumar, S. and Sidransky, D.  Tumor-specific changes in mtDNA content in human cancer. International Journal of Cancer. 2005.  116, 920-924. [PubMed]
19. Mambo, E., Chatterjee, A., de, S., Mayard, S., Hogue, B. A., Hoque, M. O., Dizdaroglu, M., Bohr, V. A. and Sidransky, D.  Oxidized guanine lesions and hOgg1 activity in lung cancer. Oncogene. 2005.  24, 4496-4508. [PubMed]
20. Rasmussen, A. K., Chatterjee, A., Rasmussen, L. J. and Singh, K. K.  Mitochondria-mediated nuclear mutator phenotype in Saccharomyces cerevisiae. Nucleic Acids Research. 2003.  31, 3909-3917. [PubMed]
21. Chatterjee, A. and Singh, K. K.  Uracil-DNA glycosylase-deficient yeast exhibit a mitochondrial mutator phenotype. Nucleic Acids Research. 2001. 29, 4935-4940. [PubMed]
22. Chatterjee, A. , Sagarika Kanjilal and Asok K Bhattacharyya. Purification of human seminal acrosin inhibitor and its kinetics. J. Biosciences. 1999. 24, 323-328.

 

 
My CV:   Download
 
Education 
::
Ph.D. in Biochemistry, Calcutta University, India, 1995-2000
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M.Sc. , 1993-1995
Honors and Awards
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2008, Young Clinical Scientist Award from Flight Attendant Medical Research Institute
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1998-1999 , Research Fellowship in Molecular Biology at University of Minnesota, Department of Veterinary PathoBiology, St. Paul, MN, USA
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1998, Senior Research Fellowship from Indian Council of Medical Research, New Delhi, India
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1996-1997, Research Fellowship from East India Pharmaceuticals, Calcutta, India
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Guest Editor: Special Issue of Journal of Oncology on “Cigarette smoke and Cancer” , Reviewer: Hematological Oncology, PLOS One
Member
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American Association for Cancer Research
  Last modified on : Jul 1, 2011
India Cancer Research Database has been developed by the Institute of Bioinformatics with funding from the Department of Biotechnology, Government of India.