INCREDB ID : 390
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Shrirang S Pakhale, Ph.D.
Scientific Officer 
 
Advanced Centre for Treatment Research and Education in Cancer, Tata Memorial Centre
Kharghar
Navi Mumbai - 410 208   
Maharashtra   
 
E-mail: spakhale@actrec.gov.in
Phone: 91-22-27405025
Fax:  91-22-27405085
 
Area of Specialization:
Chemical Analysis
Carcinogenesis
Biomarkers
Chemoprevention
Research Summary:
Comparative chemical analysis of tobacco / tobacco smoke for carcinogenic constituents, and their precursors and measurements of related biomarkers
In vitro effects of chemopreventive agents
 
Publications:
1.Ramchandani, A. G., Karibasappa, G. S. and Pakhale, S. S.  Antitumor-promoting effects of polyphenolic extracts from seedless and seeded Indian grapes. Journal of Environmental Pathology, Toxicology and Oncology : Official Organ of the International Society For Environmental Toxicology and Cancer. 2008.  27, 321-331. [PubMed]
2.Pakhale, S. S., Karibasappa, G. S., Ramchandani, A. G., Bhushan, B. and Sharma, A.  Scavenging effect of Indian grape polyphenols on 2,2'-diphenyl-1-picrylhydrazyl(DPPH) radical by electron spin resonance spectrometry. Indian Journal of Experimental Biology. 2007.  45, 968-973. [PubMed]
3.Thapliyal, R., Dolas, S. S., Pakhale, S. S. and Maru, G. B.  Evaluation of DNA damage in mice topically exposed to total particulate matter from mainstream and sidestream smoke from cigarettes and bidis. Mutagenesis. 2004.  19, 413-421. [PubMed]
4.Pakhale, S. S. and Maru, G. B.  Distribution of major and minor alkaloids in tobacco, mainstream and sidestream smoke of popular Indian smoking products. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 1998.  36, 1131-1138. [PubMed]
5.Pakhale, S. S., Jayant, K. and Bhide, S. V.  Chemical analysis of smoke of Indian cigarettes, bidis and other indigenous forms of smoking--levels of steam-volatile phenol, hydrogen cyanide and benzo(a)pyrene. The Indian Journal of Chest Diseases & Allied Sciences. 1990.  32, 75-81. [PubMed]
6.Pakhale, S. S., Jayant, K. and Bhide, S. V.  Total particulate matter and nicotine in Indian bidis and cigarettes: a comparative study of standard machine estimates and exposure levels in smokers in Bombay. Indian Journal of Cancer. 1989.  26, 227-232. [PubMed]
7.Nair, J., Pakhale, S. S. and Bhide, S. V.  Carcinogenic tobacco-specific nitrosamines in Indian tobacco products. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 1989.  27, 751-753. [PubMed]
8.Pakhale, S. S., Sarkar, S., Jayant, K. and Bhide, S. V.  Carcinogenicity of Indian bidi and cigarette smoke condensate in Swiss albino mice. Journal of Cancer Research and Clinical Oncology. 1988.  114, 647-649. [PubMed]
9.Nair, U. J., Pakhale, S. S., Speigelhalder, B., Preussmann, R. and Bhide, S. V.  Carcinogenic and cocarcinogenic constituents of masheri, a pyrolysed tobacco product. Indian Journal of Biochemistry & Biophysics. 1987.  24, 257-259. [PubMed]
10.Pakhale, S. S., Jayant, K. and Bhide, S. V.  Methods of reduction of harmful constituents in bidi smoke. The Indian Journal of Chest Diseases & Allied Sciences. 1985.  27, 148-152. [PubMed]
11.Shirname, L. P., Menon, M. M., Murdia, U. S., Bhide, S. V. and Pakhale, S. S.  Comparison of mutagenicity of Indian cigarettes and bidi smoke condensates. Indian Journal of Experimental Biology. 1985.  23, 145-148. [PubMed]
12.Shirname, L. P., Menon, M. M., Pakhale, S. S. and Bhide, S. V.  Mutagenicity of smoke condensate of bidi--an indigenous cigarette of India. Carcinogenesis. 1984.  5, 1179-1181. [PubMed]
 
Education 
::
Ph.D. in Biochemistry
::
M.Sc. in Organic Chemistry
Honors and Awards
::
February 2006, Prize for best poster presentation at 31st Annual Conference of "Environmental Mutagen Society of Indiaā€¯
  Last modified on : Aug 19, 2011
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